Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 muta...
Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues
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Publisher
Washington: National Academy of Sciences
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Language
English
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Washington: National Academy of Sciences
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Current sequencing methods are error-prone, which precludes the identification of low frequency mutations for early cancer detection. Duplex sequencing is a sequencing technology that decreases errors by scoring mutations present only in both strands of DNA. Our aim was to determine whether duplex sequencing could detect extremely rare cancer cells...
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Full title
Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues
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TN_cdi_proquest_journals_1795024245
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1795024245
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ISSN
0027-8424
E-ISSN
1091-6490
