Multilineage transduction of resident lung cells in vivo by AAV2/8 for [alpha]1-antitrypsin gene the...
Multilineage transduction of resident lung cells in vivo by AAV2/8 for [alpha]1-antitrypsin gene therapy
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Milwaukee: Elsevier Limited
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Language
English
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Publisher
Milwaukee: Elsevier Limited
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Contents
In vivo gene delivery has long represented an appealing potential treatment approach for monogenic diseases such as α1 -antitrypsin deficiency (AATD) but has proven challenging to achieve in practice. Alternate pseudotyping of recombinant adeno-associated virus (AAV) vectors is producing vectors with increasingly heterogeneous tropic specificity, g...
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Multilineage transduction of resident lung cells in vivo by AAV2/8 for [alpha]1-antitrypsin gene therapy
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TN_cdi_proquest_journals_1800270990
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1800270990
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E-ISSN
2329-0501
DOI
10.1038/mtm.2016.42