Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the
Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the
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Publisher
Washington: National Academy of Sciences
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Language
English
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Publisher
Washington: National Academy of Sciences
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Contents
Genes encoding angiotensin-converting enzymes (Ace and Ace2) are essential for heart function regulation. Cardiac stress enhances Ace, but suppresses Ace2, expression in the heart, leading to a net production of angiotensin II that promotes cardiac hypertrophy and fibrosis. The regulatory mechanism that underlies the Ace2-to-Ace pathological switch...
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Full title
Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the
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TN_cdi_proquest_journals_1825439205
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1825439205
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ISSN
0027-8424
E-ISSN
1091-6490
