Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sick...
Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and [Beta]-thalassemia
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Publisher
Washington: National Academy of Sciences
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Language
English
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Washington: National Academy of Sciences
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Contents
Hereditary persistence of fetal hemoglobin (HPFH) is a condition in some individuals who have a high level of fetal hemoglobin throughout life. Individuals with compound heterozygous β-thalassemia or sickle cell disease (SCD) and HPFH have milder clinical manifestations. Using RNA-guided clustered regularly interspaced short palindromic repeats-ass...
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Full title
Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and [Beta]-thalassemia
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TN_cdi_proquest_journals_1825439334
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1825439334
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ISSN
0027-8424
E-ISSN
1091-6490
