Prodruggability of carbohydrates — oral FimH antagonists
Prodruggability of carbohydrates — oral FimH antagonists
About this item
Full title
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Publisher
Ottawa: NRC Research Press
Journal title
Language
English
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Publisher
Ottawa: NRC Research Press
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Scope and Contents
Contents
The bacterial lectin FimH is a promising therapeutic target for the nonantibiotic prevention and treatment of urinary tract infections. In this communication, an ester prodrug approach is described to achieve oral bioavailability for FimH antagonists. By introducing short-chain acyl promoieties at the C-6 position of a biphenyl α-
d
-mannopyr...
Alternative Titles
Full title
Prodruggability of carbohydrates — oral FimH antagonists
Authors, Artists and Contributors
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TN_cdi_proquest_journals_1842390099
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1842390099
Other Identifiers
ISSN
0008-4042
E-ISSN
1480-3291
DOI
10.1139/cjc-2015-0582
