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Using a gene expression signature when controversy exists regarding the indication for adjuvant syst...

Using a gene expression signature when controversy exists regarding the indication for adjuvant syst...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1844715597

Using a gene expression signature when controversy exists regarding the indication for adjuvant systemic treatment reduces the proportion of patients receiving adjuvant chemotherapy: a nationwide study

About this item

Full title

Using a gene expression signature when controversy exists regarding the indication for adjuvant systemic treatment reduces the proportion of patients receiving adjuvant chemotherapy: a nationwide study

Publisher

New York: Elsevier Inc

Journal title

Genetics in medicine, 2016-07, Vol.18 (7), p.720-726

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

The Dutch national guideline advises use of gene-expression signatures, such as the 70-gene signature (70-GS), in case of ambivalence regarding the benefit of adjuvant chemotherapy (CT). In this nationwide study, the impact of 70-GS use on the administration of CT in early breast cancer patients with a dubious indication for CT is assessed.
Pati...

Alternative Titles

Full title

Using a gene expression signature when controversy exists regarding the indication for adjuvant systemic treatment reduces the proportion of patients receiving adjuvant chemotherapy: a nationwide study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1844715597

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1844715597

Other Identifiers

ISSN

1098-3600

E-ISSN

1530-0366

DOI

10.1038/gim.2015.152

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