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Extracellular matrix loss in chondrocytes after exposure to interleukin-1[beta] in NADPH oxidase-dep...

Extracellular matrix loss in chondrocytes after exposure to interleukin-1[beta] in NADPH oxidase-dep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1880744076

Extracellular matrix loss in chondrocytes after exposure to interleukin-1[beta] in NADPH oxidase-dependent manner

About this item

Full title

Extracellular matrix loss in chondrocytes after exposure to interleukin-1[beta] in NADPH oxidase-dependent manner

Publisher

Heidelberg: Springer

Journal title

Cell and tissue research, 2017-04, Vol.368 (1), p.135

Language

English

Formats

Publication information

Publisher

Heidelberg: Springer

More information

Scope and Contents

Contents

Osteoarthritis is a degenerative joint disease caused by excessive death of chondrocytes and loss of the extracellular matrix (ECM) in articular cartilage. We previously reported that reactive oxygen species (ROS) generated by the NADPH oxidase (NOX) isoform NOX-2 are involved in chondrocyte death induced by interleukin-1[beta] (IL-1[beta]). In thi...

Alternative Titles

Full title

Extracellular matrix loss in chondrocytes after exposure to interleukin-1[beta] in NADPH oxidase-dependent manner

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1880744076

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1880744076

Other Identifiers

ISSN

0302-766X

E-ISSN

1432-0878

DOI

10.1007/s00441-016-2551-2

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