Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1^sup G93A^ ALS Mice
Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1^sup G93A^ ALS Mice
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Author / Creator
Wang, Wan , Duan, Weisong , Wang, Ying , Wen, Di , Liu, Yakun , Li, Zhongyao , Hu, Haojie , Cui, Hongying , Cui, Can , Lin, Huiqian and Li, Chunyan
Publisher
New York: Springer Nature B.V
Journal title
Language
English
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Publisher
New York: Springer Nature B.V
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Contents
Amyotrophic lateral sclerosis (ALS) is an adult-onset, irreversible neurodegenerative disease that leads to progressive paralysis and inevitable death 3-5 years after diagnosis. The mechanisms underlying this process remain unknown, but new evidence indicates that accumulating levels of d-serine result from the downregulation of d-amino acid oxidas...
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Full title
Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1^sup G93A^ ALS Mice
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Record Identifier
TN_cdi_proquest_journals_1882766474
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1882766474
Other Identifiers
ISSN
0364-3190
E-ISSN
1573-6903
DOI
10.1007/s11064-016-2131-6
