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A distinct role for Lgr^sup 5+^ stem cells in primary and metastatic colon cancer

A distinct role for Lgr^sup 5+^ stem cells in primary and metastatic colon cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1884787719

A distinct role for Lgr^sup 5+^ stem cells in primary and metastatic colon cancer

About this item

Full title

A distinct role for Lgr^sup 5+^ stem cells in primary and metastatic colon cancer

Publisher

London: Nature Publishing Group

Journal title

Nature (London), 2017-03, Vol.543 (7647), p.676

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group

More information

Scope and Contents

Contents

Cancer stem cells (CSCs) have been hypothesized to represent the driving force behind tumour progression and metastasis, making them attractive cancer targets. However, conclusive experimental evidence for their functional relevance is still lacking for most malignancies. Here we show that the leucine-rich repeat-containing G-protein-coupled recept...

Alternative Titles

Full title

A distinct role for Lgr^sup 5+^ stem cells in primary and metastatic colon cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1884787719

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1884787719

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature21713

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