Novel mechanism of enhancing IRE1[alpha]-XBP1 signalling via the PERK-ATF4 pathway
Novel mechanism of enhancing IRE1[alpha]-XBP1 signalling via the PERK-ATF4 pathway
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London: Nature Publishing Group
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English
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London: Nature Publishing Group
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Mammalian inositol-requiring enzyme 1α (IRE1α) is the most conserved of all endoplasmic reticulum (ER) stress sensors, which includes activating transcription factor (ATF) 6 and double-stranded RNA-dependent protein kinase (PKR)-like ER kinase (PERK). IRE1α has been known to splice X-box binding protein 1 (XBP1) mRNA, which is induced by ATF6 under...
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Full title
Novel mechanism of enhancing IRE1[alpha]-XBP1 signalling via the PERK-ATF4 pathway
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TN_cdi_proquest_journals_1898676996
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1898676996
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E-ISSN
2045-2322
DOI
10.1038/srep24217
