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Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid

Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1899718197

Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid

About this item

Full title

Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Archives of toxicology, 2017-06, Vol.91 (6), p.2365-2374

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Perfluorocarboxylic acids (PFCAs) including perfluorooctanoic acid (PFOA) are environmental pollutants showing high accumulation, thermochemical stability and hepatocarcinogenicity. Peroxisome proliferator-activated receptor α is suggested to mediate their toxicities, but the precise mechanism remains unclear. Previous reports also imply a possible...

Alternative Titles

Full title

Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1899718197

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1899718197

Other Identifiers

ISSN

0340-5761

E-ISSN

1432-0738

DOI

10.1007/s00204-016-1888-3

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