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Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis indu...

Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis indu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1899725520

Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis induced by oxidative stress

About this item

Full title

Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis induced by oxidative stress

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Archives of toxicology, 2017-06, Vol.91 (6), p.2391-2403

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

In previous studies, we showed that the pro-oxidant model agent
tert
-butyl hydroperoxide (
t
BuOOH) induces alterations in hepatocanalicular secretory function by activating Ca
2+
-dependent protein kinase C isoforms (cPKC), via F-actin disorganization followed by endocytic internalization of canalicular transporters relevant to...

Alternative Titles

Full title

Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis induced by oxidative stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1899725520

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1899725520

Other Identifiers

ISSN

0340-5761

E-ISSN

1432-0738

DOI

10.1007/s00204-016-1898-1

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