Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis indu...
Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis induced by oxidative stress
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
In previous studies, we showed that the pro-oxidant model agent
tert
-butyl hydroperoxide (
t
BuOOH) induces alterations in hepatocanalicular secretory function by activating Ca
2+
-dependent protein kinase C isoforms (cPKC), via F-actin disorganization followed by endocytic internalization of canalicular transporters relevant to...
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Full title
Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis induced by oxidative stress
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TN_cdi_proquest_journals_1899725520
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1899725520
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ISSN
0340-5761
E-ISSN
1432-0738
DOI
10.1007/s00204-016-1898-1