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FRI0301 Assessment of the Effect of 12 Months Administration of Denosumab in Patients with Rheumatic...

FRI0301 Assessment of the Effect of 12 Months Administration of Denosumab in Patients with Rheumatic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1901773004

FRI0301 Assessment of the Effect of 12 Months Administration of Denosumab in Patients with Rheumatic Diseases – Bone Mineral Density Increase in Lumbar Spine is Negatively Correlated with Baseline Oral Prednisolone Dose and Predicted by Decreasing Rate of Serum Undercarboxylated Osteocalcin at 6 Months

About this item

Full title

FRI0301 Assessment of the Effect of 12 Months Administration of Denosumab in Patients with Rheumatic Diseases – Bone Mineral Density Increase in Lumbar Spine is Negatively Correlated with Baseline Oral Prednisolone Dose and Predicted by Decreasing Rate of Serum Undercarboxylated Osteocalcin at 6 Months

Publisher

Kidlington: Elsevier Limited

Journal title

Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.533

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Limited

More information

Scope and Contents

Contents

BackgroundReceptor activator of nuclear factor kappa-B ligand (RANKL) is a key inducer of osteoclast differentiation and activation, which plays a crucial role in osteoporosis and bone erosion of rheumatic diseases. Denosumab (DSM) is an anti-RANKL antibody approved for the treatment of postmenopausal osteoporosis, while its effect in rheumatic dis...

Alternative Titles

Full title

FRI0301 Assessment of the Effect of 12 Months Administration of Denosumab in Patients with Rheumatic Diseases – Bone Mineral Density Increase in Lumbar Spine is Negatively Correlated with Baseline Oral Prednisolone Dose and Predicted by Decreasing Rate of Serum Undercarboxylated Osteocalcin at 6 Months

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1901773004

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1901773004

Other Identifiers

ISSN

0003-4967

E-ISSN

1468-2060

DOI

10.1136/annrheumdis-2015-eular.2658

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