OP0253 Galectin 3 Defiency Altered Chondrocyte Primary Cilia formation and Exacerbated Cartilage Des...
OP0253 Galectin 3 Defiency Altered Chondrocyte Primary Cilia formation and Exacerbated Cartilage Destruction
About this item
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Author / Creator
Forien, M. , Hafsia, N. , Poirier, F. , Delacour, D. , Reboul, P. , Cohen-Solal, M. , Lioté, F. and Ea, H.-K.
Publisher
Kidlington: Elsevier Limited
Journal title
Language
English
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Publisher
Kidlington: Elsevier Limited
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Scope and Contents
Contents
BackgroundOsteoarthritis (OA) is a multifaceted joint disease defined by cartilage degradation leading to joint destruction. Ageing and mechanical overload are the two main risk factors of OA. Primary cilium, located at the surface of chondrocytes, is an organelle that may act as a mechanosensor. Galectin 3 (gal-3) is a 30-kDa lectin expressed in s...
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Full title
OP0253 Galectin 3 Defiency Altered Chondrocyte Primary Cilia formation and Exacerbated Cartilage Destruction
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Author / Creator
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Record Identifier
TN_cdi_proquest_journals_1901773396
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1901773396
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2015-eular.4847