SAT0038 Osteoclasts Activate Chondrocyte Catabolism Through S1P Production
SAT0038 Osteoclasts Activate Chondrocyte Catabolism Through S1P Production
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Publisher
Kidlington: Elsevier Limited
Journal title
Language
English
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Publisher
Kidlington: Elsevier Limited
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Contents
BackgroundSubchondral bone features accompanied all stages development of osteoarthritis (OA). We have previously demonstrated that high osteoclastogenesis and bone remodeling is observed at the initiation of OA, while inhibition of osteoclast function prevents bone and cartilage catabolism in murine OA models.ObjectivesOur purpose was to evaluate...
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Full title
SAT0038 Osteoclasts Activate Chondrocyte Catabolism Through S1P Production
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Author / Creator
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TN_cdi_proquest_journals_1901778282
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1901778282
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ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2015-eular.4432