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Placebo-controlled phase II study of vitamin K3 cream for the treatment of cetuximab-induced rash

Placebo-controlled phase II study of vitamin K3 cream for the treatment of cetuximab-induced rash

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1902403742

Placebo-controlled phase II study of vitamin K3 cream for the treatment of cetuximab-induced rash

About this item

Full title

Placebo-controlled phase II study of vitamin K3 cream for the treatment of cetuximab-induced rash

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Supportive care in cancer, 2017-07, Vol.25 (7), p.2179-2185

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Cetuximab inhibits the epidermal growth factor receptor (EGFR), and papulopustular eruptions is a frequent side effect. Vitamin K3 (menadione) has preclinically shown to be a potential activator of the EGFR by phosphorylating the receptor (pEGFR). The present randomised study investigated the effect of a vitamin K3 cream on cetuximab-ind...

Alternative Titles

Full title

Placebo-controlled phase II study of vitamin K3 cream for the treatment of cetuximab-induced rash

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1902403742

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1902403742

Other Identifiers

ISSN

0941-4355

E-ISSN

1433-7339

DOI

10.1007/s00520-017-3623-x

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