The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3ß inhibition
The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3ß inhibition
About this item
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Author / Creator
Varano, Gabriele , Raffel, Simon , Sormani, Martina , Zanardi, Federica , Lonardi, Silvia , Zasada, Christin , Perucho, Laura , Petrocelli, Valentina , Haake, Andrea , Lee, Albert K , Bugatti, Mattia , Paul, Ulrike , Van Anken, Eelco , Pasqualucci, Laura , Rabadan, Raul , Siebert, Reiner , Kempa, Stefan , Ponzoni, Maurilio , Facchetti, Fabio , Rajewsky, Klaus and Casola, Stefano
Publisher
London: Nature Publishing Group
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group
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More information
Scope and Contents
Contents
Similar to resting mature B cells, where the B-cell antigen receptor (BCR) controls cellular survival1-3, surface BCR expression is conserved in most mature B-cell lymphomas. The identification of activating BCR mutations and the growth disadvantage upon BCR knockdown of cells of certain lymphoma entities has led to the view that BCR signalling is...
Alternative Titles
Full title
The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3ß inhibition
Authors, Artists and Contributors
Author / Creator
Raffel, Simon
Sormani, Martina
Zanardi, Federica
Lonardi, Silvia
Zasada, Christin
Perucho, Laura
Petrocelli, Valentina
Haake, Andrea
Lee, Albert K
Bugatti, Mattia
Paul, Ulrike
Van Anken, Eelco
Pasqualucci, Laura
Rabadan, Raul
Siebert, Reiner
Kempa, Stefan
Ponzoni, Maurilio
Facchetti, Fabio
Rajewsky, Klaus
Casola, Stefano
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1909734027
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1909734027
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.103B/nature22353
