TFEB-VEGFA (6p21.1) co-amplified renal cell carcinoma: a distinct entity with potential implications...
TFEB-VEGFA (6p21.1) co-amplified renal cell carcinoma: a distinct entity with potential implications for clinical management
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Publisher
New York: Elsevier Inc
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Language
English
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New York: Elsevier Inc
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Contents
A subset of renal cell carcinomas shows TFEB overexpression secondary to MALAT1-TFEB gene fusion. As alternate mechanisms of TFEB overexpression are likely to have the same effect, we sought to determine the frequency of amplification of TFEB and the adjacent VEGFA gene at 6p21.1. As patients with metastatic renal cell carcinomas are managed with a...
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Full title
TFEB-VEGFA (6p21.1) co-amplified renal cell carcinoma: a distinct entity with potential implications for clinical management
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TN_cdi_proquest_journals_1914824945
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1914824945
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ISSN
0893-3952
E-ISSN
1530-0285
DOI
10.1038/modpathol.2017.24
