A106 HOST-PATHOGEN INTERACTIONS: Medi3902 Targeting P. AerugINOSa Virulence Factors Pcrv And Psl For...
A106 HOST-PATHOGEN INTERACTIONS: Medi3902 Targeting P. AerugINOSa Virulence Factors Pcrv And Psl For The Prevention Of Pulmonary Colonization During Mechanical Ventilation
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Bassi, G Li , Aguilera, E , Senussi, T , Iodone, F A , Motos, A , Chiurazzi, C , Travierso, C , Amaro, R , Hua, Y , Bobi, J , Alejos, R Martinez , Rigol, M , Comino, O , Ranzani, O T , Barat, L Fernandez , Di Giandomenico, A , Stover, C K , Pelosi, P , Antonelli, M and Torres, A
Publisher
New York: American Thoracic Society
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English
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New York: American Thoracic Society
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Introduction: PcrV is a component of the type-3 P. aeruginosa secretion system, which allows injection of cytotoxic factors into host cells; Psl is implicated in the initial colonization, biofilm establishment, and immune evasion. Conclusions: In a porcine model of MV at risk of P. aeruginosa pulmonary colonization, prophylaxis with MEDI3902 result...
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A106 HOST-PATHOGEN INTERACTIONS: Medi3902 Targeting P. AerugINOSa Virulence Factors Pcrv And Psl For The Prevention Of Pulmonary Colonization During Mechanical Ventilation
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TN_cdi_proquest_journals_1926716574
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1926716574
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ISSN
1073-449X
E-ISSN
1535-4970