D27 I WANNA BE YOUR ... NOVEL MECHANISTIC INSIGHT INTO PULMONARY VASCULAR DISEASE: Targeting Tmem16a...
D27 I WANNA BE YOUR ... NOVEL MECHANISTIC INSIGHT INTO PULMONARY VASCULAR DISEASE: Targeting Tmem16a Might Represent A Novel Reverse Remodeling Therapy In Pulmonary Arterial Hypertension
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Olschewski, A , Papp, R , Nagaraj, C , Nagy, B , Balint, Z , Kwapiszewska, G , Stacher-Priehse, E , Kovacs, G , Klepetko, W , Ghanim, B , Wygrecka, M , Didiasova, M and Olschewski, H
Publisher
New York: American Thoracic Society
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Language
English
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Publisher
New York: American Thoracic Society
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Contents
RATIONALE The Ca2+ activated Cl- channel TMEM16A was found upregulated in a non-targeted gene expression survey on pulmonary arteries (PA) and pulmonary arterial smooth muscle cells (PASMC) of patients with idiopathic pulmonary hypertension (IPAH), compared to healthy donors. The resulting depolarization, most probably through the activation of vol...
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Full title
D27 I WANNA BE YOUR ... NOVEL MECHANISTIC INSIGHT INTO PULMONARY VASCULAR DISEASE: Targeting Tmem16a Might Represent A Novel Reverse Remodeling Therapy In Pulmonary Arterial Hypertension
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TN_cdi_proquest_journals_1926719917
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1926719917
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ISSN
1073-449X
E-ISSN
1535-4970