CK2 is a key regulator of SLC4A2-mediated Cl^sup -^/HCO3 ^sup -^ exchange in human airway epithelia
CK2 is a key regulator of SLC4A2-mediated Cl^sup -^/HCO3 ^sup -^ exchange in human airway epithelia
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Heidelberg: Springer Nature B.V
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Language
English
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Heidelberg: Springer Nature B.V
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Contents
Transepithelial bicarbonate secretion by human airway submucosal glands and surface epithelial cells is crucial to maintain the pH-sensitive innate defence mechanisms of the lung. cAMP agonists stimulate HCO3 - secretion via coordinated increases in basolateral HCO3 - influx and accumulation, as well as CFTR-dependent HCO3 - efflux at the luminal m...
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Full title
CK2 is a key regulator of SLC4A2-mediated Cl^sup -^/HCO3 ^sup -^ exchange in human airway epithelia
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TN_cdi_proquest_journals_1927950752
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1927950752
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ISSN
0031-6768
E-ISSN
1432-2013
DOI
10.1007/s00424-017-1981-3
