Imidazole inhibits autophagy flux by blocking autophagic degradation and triggers apoptosis via incr...
Imidazole inhibits autophagy flux by blocking autophagic degradation and triggers apoptosis via increasing FoxO3a-Bim expression
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Athens: D.A. Spandidos
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English
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Athens: D.A. Spandidos
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Imidazole, an organic alkaloid, is an important pharmacophore in drug discovery. Anti-neoplastic potential of imidazole derivatives has been documented in several studies; however, mechanisms by which tumor cells respond to these stimuli remain to be elucidated. Autophagy and apoptosis have key roles in tumorigenesis and tumor treatment. In this st...
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Imidazole inhibits autophagy flux by blocking autophagic degradation and triggers apoptosis via increasing FoxO3a-Bim expression
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TN_cdi_proquest_journals_1932313483
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932313483
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ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2014.2771