Downregulation of Nrf2 promotes radiation-induced apoptosis through Nrf2 mediated Notch signaling in...
Downregulation of Nrf2 promotes radiation-induced apoptosis through Nrf2 mediated Notch signaling in non-small cell lung cancer cells
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Author / Creator
ZHAO, QIUYUE , MAO, AIHONG , YAN, JIAWEI , SUN, CHAO , DI, CUIXIA , ZHOU, XIN , LI, HONGYAN , GUO, RUOSHUI and ZHANG, HONG
Publisher
Athens: D.A. Spandidos
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Language
English
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Publisher
Athens: D.A. Spandidos
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Contents
The nuclear factor erythroid-2-related factor 2 (Nrf2) is a crucial regulator of the cellular antioxidant system. Nrf2 is often constitutively activated in non-small cell lung cancer (NSCLC) cell lines, which promotes cytoprotection against oxidative stress and xenobiotics. Notch1 signaling is critically implicated in cell fate determination. It ha...
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Full title
Downregulation of Nrf2 promotes radiation-induced apoptosis through Nrf2 mediated Notch signaling in non-small cell lung cancer cells
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TN_cdi_proquest_journals_1932325960
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932325960
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ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2015.3301