Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human bre...
Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells
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Athens: D.A. Spandidos
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Language
English
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Publisher
Athens: D.A. Spandidos
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Contents
Sirtuins (SIRTs), NAD+-dependent class III histone deacetylases (HDACs), play an important role in the regulation of cell division, survival and senescence. Although a number of effective SIRT inhibitors have been developed, little is known about the specific mechanisms of their anticancer activity. In this study, we investigated the anticancer eff...
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Full title
Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells
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TN_cdi_proquest_journals_1932326469
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932326469
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ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2012.1534
