TWEAK/Fn14 signaling mediates gastric cancer cell resistance to 5-fluorouracil via NF-κB activation
TWEAK/Fn14 signaling mediates gastric cancer cell resistance to 5-fluorouracil via NF-κB activation
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Publisher
Athens: D.A. Spandidos
Journal title
Language
English
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Publisher
Athens: D.A. Spandidos
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Scope and Contents
Contents
Chemoresistance is one of the most serious problems in the treatment of cancer. In the present study, we show that Fn14 promotes resistance to 5-fluorouracil (5-FU) in gastric cancer (GC). We found that 5-FU treatment upregulated Fn14 expression in various cancer cell lines, including GC cell lines, and that knockdown of Fn14 using shRNA accelerate...
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Full title
TWEAK/Fn14 signaling mediates gastric cancer cell resistance to 5-fluorouracil via NF-κB activation
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TN_cdi_proquest_journals_1932330565
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932330565
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ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2013.2211
