RNAi gene therapy of SiHa cells via targeting human TERT induces growth inhibition and enhances radi...
RNAi gene therapy of SiHa cells via targeting human TERT induces growth inhibition and enhances radiosensitivity
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Publisher
Athens: D.A. Spandidos
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Language
English
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Athens: D.A. Spandidos
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Contents
Telomerase activity (TA) is reactivated in more than 90% of all human malignant tumors and normal somatic cells that lack TA. Thus, human TERT (hTERT) is a promising target in malignant tumor treatment. RNA interference is a powerful tool for gene silencing. In this study, we constructed siRNA#1-4 to knock down hTERT. All siRNAs were able to downre...
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Full title
RNAi gene therapy of SiHa cells via targeting human TERT induces growth inhibition and enhances radiosensitivity
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TN_cdi_proquest_journals_1932331490
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932331490
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ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2013.2051
