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Matrix metalloproteinase-mediation of tumor targeting human recombinant tumor necrosis factor-α fusi...

Matrix metalloproteinase-mediation of tumor targeting human recombinant tumor necrosis factor-α fusi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932472801

Matrix metalloproteinase-mediation of tumor targeting human recombinant tumor necrosis factor-α fusion protein

About this item

Full title

Matrix metalloproteinase-mediation of tumor targeting human recombinant tumor necrosis factor-α fusion protein

Publisher

Greece: D.A. Spandidos

Journal title

Molecular medicine reports, 2015-08, Vol.12 (2), p.2035-2042

Language

English

Formats

Publication information

Publisher

Greece: D.A. Spandidos

More information

Scope and Contents

Contents

The aim of the present study was to use genetic engineering in order to establish an efficient tumor necrosis factor (TNF)-α fusion protein with low toxicity, which may be used to target tumors. Four types of matrix metalloproteinase (MMP)-mediated tumor targeting human recombinant TNF-α (rhTNF-α) fusion protein vectors were constructed. These were...

Alternative Titles

Full title

Matrix metalloproteinase-mediation of tumor targeting human recombinant tumor necrosis factor-α fusion protein

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1932472801

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932472801

Other Identifiers

ISSN

1791-2997

E-ISSN

1791-3004

DOI

10.3892/mmr.2015.3639

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