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Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog...

Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932671662

Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog signaling pathway

About this item

Full title

Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog signaling pathway

Publisher

Greece: D.A. Spandidos

Journal title

Oncology reports, 2016-02, Vol.35 (2), p.912-922

Language

English

Formats

Publication information

Publisher

Greece: D.A. Spandidos

More information

Scope and Contents

Contents

Breast cancer stem cells (BCSCs) are believed to be responsible for tumor chemoresistance, recurrence, and metastasis formation. Salinomycin (SAL), a carboxylic polyether ionophore, has been reported to act as a selective breast CSC inhibitor. However, the molecular mechanisms underlying SAL-induced cytotoxicity on BCSCs remain unclear. The Hedgeho...

Alternative Titles

Full title

Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog signaling pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1932671662

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1932671662

Other Identifiers

ISSN

1021-335X

E-ISSN

1791-2431

DOI

10.3892/or.2015.4434

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