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Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection

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Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1936102142

Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection

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England: BMJ Publishing Group LTD

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Contents

ObjectiveAs pathogen sensors, Toll-like receptors (TLR) play a role in the first defence line during HCV infection. However, the impact of the DNA sensor TLR9 on the natural course of HCV infection is unknown. To address this, TLR9 promoter polymorphisms (single nucleotide polymorphisms (SNPs)) rs187084 and rs5743836 were investigated for their eff...

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Full title

Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection

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TN_cdi_proquest_journals_1936102142

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1936102142

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ISSN

0017-5749

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2015-310239

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