Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion
Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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Contents
While many perceive mammalian cell culture-based manufacturing for biopharmaceuticals an established technology, numerous open questions remain to be solved. Genetic diversity and mutation rates in CHO cells have been underestimated since progeny of a clonal CHO cell become genetically diverse with each cell division. This is an important issue sin...
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Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion
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TN_cdi_proquest_journals_1939785454
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1939785454
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ISSN
2227-9717
E-ISSN
2227-9717
DOI
10.3390/pr5020020