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Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion

Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1939785454

Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion

About this item

Full title

Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion

Author / Creator

Publisher

Basel: MDPI AG

Journal title

Processes, 2017-06, Vol.5 (2), p.20

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

While many perceive mammalian cell culture-based manufacturing for biopharmaceuticals an established technology, numerous open questions remain to be solved. Genetic diversity and mutation rates in CHO cells have been underestimated since progeny of a clonal CHO cell become genetically diverse with each cell division. This is an important issue sin...

Alternative Titles

Full title

Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1939785454

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1939785454

Other Identifiers

ISSN

2227-9717

E-ISSN

2227-9717

DOI

10.3390/pr5020020

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