Tumor-penetrating peptide fused to a pro-apoptotic peptide facilitates effective gastric cancer ther...
Tumor-penetrating peptide fused to a pro-apoptotic peptide facilitates effective gastric cancer therapy
About this item
Full title
Author / Creator
Huang, Ying , Li, Xihan , Sha, Huizi , Zhang, Lianru , Bian, Xinyu , Han, Xiao and Liu, Baorui
Publisher
Greece: D.A. Spandidos
Journal title
Language
English
Formats
Publication information
Publisher
Greece: D.A. Spandidos
Subjects
More information
Scope and Contents
Contents
KLA (sequence, KLAKLAKKLAKLAK) is a peptide which leads to programmed cell death by disrupting the mitochondrial membrane. However, low penetration in tumors greatly limits its application and efficacy. To develop a KLA-based cancer therapy, KLA-iRGD, a recombinant protein was constructed. It consists of the KLA peptide and iRGD (CRGDKGPDC), a tumo...
Alternative Titles
Full title
Tumor-penetrating peptide fused to a pro-apoptotic peptide facilitates effective gastric cancer therapy
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1941291394
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1941291394
Other Identifiers
ISSN
1021-335X
E-ISSN
1791-2431
DOI
10.3892/or.2017.5440
