Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase [beta]
Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase [beta]
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New York: Springer Nature B.V
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English
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New York: Springer Nature B.V
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DNA polymerase [beta] (Pol[beta]) has been implicated in base excision repair in mammalian cells. However, the physiological significance of this enzyme in the body remains unclear. Here, we demonstrate that mice carrying a targeted disruption of the Pol[beta] gene showed growth retardation and died of a respiratory failure immediately after the bi...
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Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase [beta]
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TN_cdi_proquest_journals_195269476
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_195269476
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0261-4189
E-ISSN
1460-2075