Notch3 and pre-TCR interaction unveils distinct NF-[kappa]B pathways in T-cell development and leuke...
Notch3 and pre-TCR interaction unveils distinct NF-[kappa]B pathways in T-cell development and leukemia
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New York: Springer Nature B.V
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English
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New York: Springer Nature B.V
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Notch signaling plays a critical role in T-cell differentiation and leukemogenesis. We previously demonstrated that, while pre-TCR is required for thymocytes proliferation and leukemogenesis, it is dispensable for thymocyte differentiation in Notch3-transgenic mice. Notch3-transgenic premalignant thymocytes and T lymphoma cells overexpress pTalpha/...
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Notch3 and pre-TCR interaction unveils distinct NF-[kappa]B pathways in T-cell development and leukemia
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TN_cdi_proquest_journals_195274036
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_195274036
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ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/sj.emboj.7600996
