Log in to save to my catalogue

Rhein suppresses matrix metalloproteinase production by regulating the Rac1/ROS/MAPK/AP-1 pathway in...

Rhein suppresses matrix metalloproteinase production by regulating the Rac1/ROS/MAPK/AP-1 pathway in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1957649295

Rhein suppresses matrix metalloproteinase production by regulating the Rac1/ROS/MAPK/AP-1 pathway in human ovarian carcinoma cells

About this item

Full title

Rhein suppresses matrix metalloproteinase production by regulating the Rac1/ROS/MAPK/AP-1 pathway in human ovarian carcinoma cells

Publisher

Athens: Spandidos Publications

Journal title

International journal of oncology, 2017-03, Vol.50 (3), p.933-941

Language

English

Formats

Publication information

Publisher

Athens: Spandidos Publications

More information

Scope and Contents

Contents

Matrix metalloproteinases (MMPs) are a family of calcium-dependent zinc-containing endopeptidases, which play an integral role in migration and invasion of ovarian cancer. Rac1 proteins might mostly influence cell migration and invasion by generating endogenous reactive oxygen species. Therefore, inhibiting MMPs and regulating the Rac1/ROS/MAPK/AP-...

Alternative Titles

Full title

Rhein suppresses matrix metalloproteinase production by regulating the Rac1/ROS/MAPK/AP-1 pathway in human ovarian carcinoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1957649295

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1957649295

Other Identifiers

ISSN

1019-6439

E-ISSN

1791-2423

DOI

10.3892/ijo.2017.3853

How to access this item