Identification of the quinolinedione inhibitor binding site in Cdc25 phosphatase B through docking a...
Identification of the quinolinedione inhibitor binding site in Cdc25 phosphatase B through docking and molecular dynamics simulations
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Cham: Springer International Publishing
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English
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Cham: Springer International Publishing
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Cdc25 phosphatase B, a potential target for cancer therapy, is inhibited by a series of quinones. The binding site and mode of quinone inhibitors to Cdc25B remains unclear, whereas this information is important for structure-based drug design. We investigated the potential binding site of NSC663284 [DA3003-1 or 6-chloro-7-(2-morpholin-4-yl-ethylami...
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Identification of the quinolinedione inhibitor binding site in Cdc25 phosphatase B through docking and molecular dynamics simulations
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TN_cdi_proquest_journals_1965553765
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1965553765
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ISSN
0920-654X
E-ISSN
1573-4951
DOI
10.1007/s10822-017-0073-y
