Pharmacokinetics and Pharmacodynamics of Afamelanotide and its Clinical Use in Treating Dermatologic...
Pharmacokinetics and Pharmacodynamics of Afamelanotide and its Clinical Use in Treating Dermatologic Disorders
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Cham: Springer International Publishing
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English
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Cham: Springer International Publishing
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Afamelanotide, the first α-melanocyte-stimulating hormone (MSH) analogue, synthesized in 1980, was broadly investigated in all aspects of pigmentation because its activity and stability were higher than the natural hormone. Afamelanotide binds to the melanocortin-1 receptor (MC1R), and MC1R signaling increases melanin synthesis, induces antioxidant...
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Pharmacokinetics and Pharmacodynamics of Afamelanotide and its Clinical Use in Treating Dermatologic Disorders
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TN_cdi_proquest_journals_1973308539
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1973308539
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ISSN
0312-5963
E-ISSN
1179-1926
DOI
10.1007/s40262-016-0501-5
