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Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy

Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1975513434

Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy

About this item

Full title

Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy

Publisher

New York: Springer US

Journal title

Bulletin of mathematical biology, 2019-09, Vol.81 (9), p.3508-3541

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Positron emission tomography, an imaging tool using radiolabeled tracers in humans and preclinical species, has been widely used in recent years in drug development, particularly in the central nervous system. One important goal of PET in drug development is assessing the occupancy of various molecular targets (e.g., receptors, transporters, enzyme...

Alternative Titles

Full title

Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1975513434

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1975513434

Other Identifiers

ISSN

0092-8240

E-ISSN

1522-9602

DOI

10.1007/s11538-017-0374-2

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