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NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell deat...

NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell deat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1983675069

NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation

About this item

Full title

NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2018-01, Vol.98 (1), p.63-78

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The goal of this study was to elucidate the functional role of Nox4 during acute kidney injury (AKI). NADPH oxidases are a major source of reactive oxygen species (ROS) in the kidney in normal and pathological conditions. Among NADPH oxidase isoforms, NADPH oxidase4 (Nox4) is highly expressed in the kidney and has an important role in kidney diseas...

Alternative Titles

Full title

NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1983675069

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1983675069

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2017.120

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