Orally administered diflunisal stabilizes transthyretin against dissociation required for amyloidoge...
Orally administered diflunisal stabilizes transthyretin against dissociation required for amyloidogenesis
About this item
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Publisher
England: Informa UK Ltd
Journal title
Language
English
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Publisher
England: Informa UK Ltd
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Scope and Contents
Contents
Objective. Rate-limiting transthyretin (TTR) tetramer dissociation and monomer misfolding enable misassembly into numerous aggregate morphologies including amyloid, a process genetically linked to and thought to cause amyloid pathology. T119M TTR trans-suppressor subunit inclusion into tetramers otherwise composed of disease-associated subunits ame...
Alternative Titles
Full title
Orally administered diflunisal stabilizes transthyretin against dissociation required for amyloidogenesis
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Record Identifier
TN_cdi_proquest_journals_198866540
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_198866540
Other Identifiers
ISSN
1350-6129
E-ISSN
1744-2818
DOI
10.1080/13506120600960882
