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Dutch, Flemish, Italian, and Arctic mutations of APP and resistance of A[beta] to physiologically re...

Dutch, Flemish, Italian, and Arctic mutations of APP and resistance of A[beta] to physiologically re...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_199031501

Dutch, Flemish, Italian, and Arctic mutations of APP and resistance of A[beta] to physiologically relevant proteolytic degradation

About this item

Full title

Dutch, Flemish, Italian, and Arctic mutations of APP and resistance of A[beta] to physiologically relevant proteolytic degradation

Publisher

London: Elsevier Limited

Journal title

The Lancet (British edition), 2003-06, Vol.361 (9373), p.1957

Language

English

Formats

Publication information

Publisher

London: Elsevier Limited

More information

Scope and Contents

Contents

The Dutch, Flemish, Italian, and Arctic mutations in the amyloid precursor protein (APP) gene encode changes within the sequence of the amyloid beta peptide (Abeta) and cause presenile cerebral amyloid angiopathy, cerebral parenchymal amyloidosis, or both. These disorders are caused by accumulation of Abeta, with no evidence of increased Abeta prod...

Alternative Titles

Full title

Dutch, Flemish, Italian, and Arctic mutations of APP and resistance of A[beta] to physiologically relevant proteolytic degradation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_199031501

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_199031501

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(03)13555-6

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