Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus
Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus
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Publisher
Kidlington: Elsevier Ltd
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Language
English
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Kidlington: Elsevier Ltd
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Summary Peripherally acting μ-opioid receptor antagonists methylnaltrexone and alvimopan are a new class of drugs designed to reverse opioid-induced side-effects on the gastrointestinal system without compromising pain relief. This article gives an overview of the pharmacology, the efficacy, and adverse effects of these drugs. Both compounds seem t...
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Full title
Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus
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TN_cdi_proquest_journals_199040178
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_199040178
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ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(09)60139-2