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Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus

Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_199040178

Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus

About this item

Full title

Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus

Publisher

Kidlington: Elsevier Ltd

Journal title

The Lancet (British edition), 2009-04, Vol.373 (9670), p.1198-1206

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Ltd

More information

Scope and Contents

Contents

Summary Peripherally acting μ-opioid receptor antagonists methylnaltrexone and alvimopan are a new class of drugs designed to reverse opioid-induced side-effects on the gastrointestinal system without compromising pain relief. This article gives an overview of the pharmacology, the efficacy, and adverse effects of these drugs. Both compounds seem t...

Alternative Titles

Full title

Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_199040178

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_199040178

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(09)60139-2

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