Identification and Characterization of a New BRCA2 Rearrangement in an Italian Family with Hereditar...
Identification and Characterization of a New BRCA2 Rearrangement in an Italian Family with Hereditary Breast and Ovarian Cancer Syndrome
About this item
Full title
Author / Creator
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
More information
Scope and Contents
Contents
Introduction
Many studies document the involvement of
BRCA1/2
gene rearrangements in genetic predisposition to breast and ovarian cancer. Large genomic rearrangements (LGRs) of
BRCA1
account for 0–27% of all disease-causing mutations in various populations, while LGRs in
BRCA2
are rarer. Here, we describe a novel
BRCA2
LG...
Alternative Titles
Full title
Identification and Characterization of a New BRCA2 Rearrangement in an Italian Family with Hereditary Breast and Ovarian Cancer Syndrome
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1990422230
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1990422230
Other Identifiers
ISSN
1177-1062
E-ISSN
1179-2000
DOI
10.1007/s40291-017-0288-6
