Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin...
Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Sacubitril/valsartan (LCZ696) is indicated for the treatment of heart failure with reduced ejection fraction. Absorption of sacubitril/valsartan and conversion of sacubitril (prodrug) to sacubitrilat (neprilysin inhibitor) was rapid with maximum plasma concentrations of sacubitril, sacubitrilat, and valsartan (angiotensin receptor blocker) reaching...
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Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor
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TN_cdi_proquest_journals_1990422638
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1990422638
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ISSN
0312-5963
E-ISSN
1179-1926
DOI
10.1007/s40262-017-0543-3