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Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, rand...

Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, rand...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1990474776

Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial

About this item

Full title

Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial

Publisher

London: Nature Publishing Group UK

Journal title

Translational psychiatry, 2018-01, Vol.8 (1), p.27-11, Article 27

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Given evidence of chronic inflammation in bipolar disorder (BD), we tested the efficacy of aspirin and minocycline as augmentation therapy for bipolar depression. Ninety-nine depressed outpatients with BD were enrolled in a 6 week, double-blind, placebo-controlled trial, and randomized to one of four groups: active minocycline (100 mg b.i.d.) + act...

Alternative Titles

Full title

Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1990474776

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1990474776

Other Identifiers

ISSN

2158-3188

E-ISSN

2158-3188

DOI

10.1038/s41398-017-0073-7

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