Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, rand...
Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Given evidence of chronic inflammation in bipolar disorder (BD), we tested the efficacy of aspirin and minocycline as augmentation therapy for bipolar depression. Ninety-nine depressed outpatients with BD were enrolled in a 6 week, double-blind, placebo-controlled trial, and randomized to one of four groups: active minocycline (100 mg b.i.d.) + act...
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Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial
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TN_cdi_proquest_journals_1990474776
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1990474776
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2158-3188
E-ISSN
2158-3188
DOI
10.1038/s41398-017-0073-7