Structure-based drug design, synthesis and biological assays of P. falciparum Atg3–Atg8 protein–prot...
Structure-based drug design, synthesis and biological assays of P. falciparum Atg3–Atg8 protein–protein interaction inhibitors
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Cham: Springer International Publishing
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English
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Cham: Springer International Publishing
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The proteins involved in the autophagy (Atg) pathway have recently been considered promising targets for the development of new antimalarial drugs. In particular, inhibitors of the protein–protein interaction (PPI) between Atg3 and Atg8 of
Plasmodium falciparum
retarded the blood- and liver-stages of parasite growth. In this paper, we used co...
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Structure-based drug design, synthesis and biological assays of P. falciparum Atg3–Atg8 protein–protein interaction inhibitors
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TN_cdi_proquest_journals_1993585097
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1993585097
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ISSN
0920-654X
E-ISSN
1573-4951
DOI
10.1007/s10822-018-0102-5