Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
The innate immune system processes pathogen-induced signals into cell fate decisions. How information is turned to decision remains unknown. By combining stochastic mathematical modelling and experimentation, we demonstrate that feedback interactions between the IRF3, NF-κB and STAT pathways lead to switch-like responses to a viral analogue, poly(I...
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Full title
Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
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TN_cdi_proquest_journals_1994394815
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1994394815
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02640-8
