Inhibition of Urokinase Activity Reduces Primary Tumor Growth and Metastasis Formation in a Murine L...
Inhibition of Urokinase Activity Reduces Primary Tumor Growth and Metastasis Formation in a Murine Lung Carcinoma Model
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Publisher
New York, NY: American Thoracic Society
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Language
English
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Publisher
New York, NY: American Thoracic Society
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Contents
Lung cancer is the most common malignancy in humans. Urokinase (uPA) plays a crucial role in carcinogenesis by facilitating tumor cell invasion and metastasis.
We investigated the effect of the highly specific urokinase inhibitor CJ-463 (benzylsulfonyl-D-Ser-Ser-4-amidinobenzylamide) on tumor growth, metastasis formation, and tumor vascularizati...
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Full title
Inhibition of Urokinase Activity Reduces Primary Tumor Growth and Metastasis Formation in a Murine Lung Carcinoma Model
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TN_cdi_proquest_journals_199610769
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_199610769
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ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.200903-0342OC
