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PI3K[delta] contributes to ER stress-associated asthma through ER-redox disturbances: the involvemen...

PI3K[delta] contributes to ER stress-associated asthma through ER-redox disturbances: the involvemen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2002468228

PI3K[delta] contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD-RIG-I-NF-[kappa]B axis

About this item

Full title

PI3K[delta] contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD-RIG-I-NF-[kappa]B axis

Publisher

Seoul: Springer Nature B.V

Journal title

Experimental & molecular medicine, 2018-02, Vol.50 (2)

Language

English

Formats

Publication information

Publisher

Seoul: Springer Nature B.V

More information

Scope and Contents

Contents

Hyperactivation of phosphoinositol 3-kinase (PI3K) has been suggested to be a potential mechanism for endoplasmic reticulum (ER) stress-enhanced airway hyperresponsiveness, and PI3K inhibitors have been examined as asthma therapeutics. However, the regulatory mechanism linking PI3K to ER stress and related pathological signals in asthma have not be...

Alternative Titles

Full title

PI3K[delta] contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD-RIG-I-NF-[kappa]B axis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2002468228

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2002468228

Other Identifiers

ISSN

1226-3613

E-ISSN

2092-6413

DOI

10.1038/emm.2017.270

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