Systematic analysis of protein turnover in primary cells
Systematic analysis of protein turnover in primary cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A better understanding of proteostasis in health and disease requires robust methods to determine protein half-lives. Here we improve the precision and accuracy of peptide ion intensity-based quantification, enabling more accurate protein turnover determination in non-dividing cells by dynamic SILAC-based proteomics. This approach allows exact dete...
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Full title
Systematic analysis of protein turnover in primary cells
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TN_cdi_proquest_journals_2002472636
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2002472636
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03106-1
