Cyclooxygenase-1–selective inhibition prolongs gestation in mice without adverse effects on the duct...
Cyclooxygenase-1–selective inhibition prolongs gestation in mice without adverse effects on the ductus arteriosus
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Preterm delivery is the leading cause of neonatal mortality and contributes significantly to infant morbidity. Classical cyclooxygenase (COX) inhibitors, such as indomethacin, which inhibit both COX-1 and COX-2, are effective for delaying premature labor, but their use is limited by serious complications to the fetus and neonate, including adverse...
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Full title
Cyclooxygenase-1–selective inhibition prolongs gestation in mice without adverse effects on the ductus arteriosus
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TN_cdi_proquest_journals_200522518
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_200522518
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI0214924
